NBA 2K22 is, at launch, a much slower-paced experience as NBA 2K21 because of the manner in which the game deals with endurance loss. If you played last year you're likely used to throwing dribbles at the top of the key to make your hands open for a 3. In contrast, if you attempted to rim running with athletes who are fast and athletic you're accustomed to breaking out and cutting through defensive lines.
When playing NBA 2K22, if you press the sprint button or use a bunch of dribble moves endurance will drop off a cliff. It wasn't quite as severe of a problem as it was in previous years because you were still able to shoot effectively when tired. In 2K22, your shot meter will decrease as you lose stamina and your release slows. This makes it harder to hit shots and provides your opponent a larger possibility to compete.
Therefore, our suggestion is to slow down. With stamina, shooting somewhat easier this year. Take advantage of that by playing a bit cautiously and you'll be able to achieve success.
In case you're an off-line player, one tip is to utilize the advancements in Visual Concepts made to AI help defense. It was the case that in past times, defenders would attack you off the pick, leaving their opponent wide and free. This allowed you to three hunt from the sidelines if you were having trouble scoring.
In 2K22 there are defenders who don't seem to crash as often making it possible to play an exciting pick-and-roll that feels more authentically like an NBA game. It's now all about reading the defense and making the right decision. If you are requesting your center to make a choice and the guy switches towards you, pass it to the big guy and let him battle smaller defenders. If they do not switch, congrats on your open court. Make it to the bucket, and shoot a layup. You could also be fouled.